What is Xeomin?
Xeomin (incobotulinumtoxinA)nis a prescription medication injected into muscles and used to temporarily improve the appearance of moderate to severe frown lines between the eyebrows(glabellar lines) in adults.
XEOMIN contains botulinum toxin type A, a protein purified from from the bacterium Clostridium botulinum.
How does XEOMIN work?
When you squint or frown, the muscles between your eyebrows contract, causing the skin to furrow and fold. Over time, as your skin ages and loses some of its elasticity, these repeated
contractions can cause persistent frown lines.
Botulinum toxin type A – the active ingredient in XEOMIN- acts on nerve endings in muscle fibers from contracting. By reducing the lines between your eye-brows.
Is XEOMIN proven?
XEOMIN was proven effective in two randomized, double-blind, multicenter, placebo-controlled clinical trails of 546 healthy, adult patients. The average age of patients in the study was 46 years. Patients received 20 Units of XEOMIN and were classified as responders if they had a 2-grade improvement on a 4-point scale as assessed by the physician and patient. Using these criteria, treatment success was higher with XEOMIN than placebo on Day 30 in both studies (60% and 48% vs. 0% for placebo in both studies). Based on these trails, XEOMIN received FDA approval for using glabellar lines in 2011.
What can i expect during treatment?
During treatment, which usually takes about 10-20 minutes, your doctor will inject XEOMIN into the muscles in your forhead that cause frown lines between your eyebrows. No anesthesia is required; however, your physicain may use a topical anesthetic or cold pack to reduce any discomfort.
When can I expect to see results?
You may begin to see visible something as early as 3-4 days after injection. The median first onset of effect eas less than a week. The maximum effect occured at 30 days. The typical duration of effect was up to 3 months in clinical trails but may last significantly longer or shorter in individual patients.